Rapid profiling of phenolic compounds of green and fermented <i>Bergenia crassifolia</i> L. leaves by UPLC-DAD-QqQ-MS and HPLC-DAD-ESI-QTOF-MS Juha-Pekka Salminen Alexander N. Shikov Maarit Karonen Olga N. Pozharitskaya Jorma Kim Valery G. Makarov Raimo Hiltunen Bertalan Galambosi 10.6084/m9.figshare.1045539.v24 https://tandf.figshare.com/articles/journal_contribution/Rapid_profiling_of_phenolic_compounds_of_green_and_fermented_i_Bergenia_crassifolia_i_L_leaves_by_UPLC_DAD_QqQ_MS_and_HPLC_DAD_ESI_QTOF_MS/1045539 <div><p><i>Bergenia crassifolia</i> L., Saxifragaceae, is an evergreen perennial plant known in traditional medicine of Russia, Mongolia and China. Polyphenols are responsible for the number of pharmacological effects of <i>Bergenia</i>. UPLC-DAD-QqQ-MS and LC-DAD-ESI-QTOF-MS were used for the rapid profiling of phenolic compounds, mainly hydrolysable tannins. Green leaves consisted of 55% ellagitannins, 29% gallic acid derivatives and 11% flavonoids, with the remaining gallic acid, arbutin, bergenin and caffeoyl quinic acid. In fermented leaves, 31% of gallic acid was found, followed with 28% ellagitannins, 18% gallic acid derivatives and 18% flavonoids, with the remaining caffeoyl quinic acid, bergenin and arbutin. Tellimagrandin I, pedunculagin, caffeoyl quinic acid, monogalloyl quinic acid, 1-<i>O</i>-galloylglucose and 1,2,6-tri-<i>O</i>-galloylglucose were identified for the very first time.</p></div> 2014-09-09 14:57:16 phenolic compounds gallic acid caffeoyl quinic acid Bergenia crassifolia L monogalloyl quinic acid