Decarboxylation of indole-3-carboxylic acids under metal-free conditions Xia Chen Xiao-Yu Zhou 10.6084/m9.figshare.11854908.v1 https://tandf.figshare.com/articles/journal_contribution/Decarboxylation_of_indole-3-carboxylic_acids_under_metal-free_conditions/11854908 <p>Two reaction systems have been developed for the decarboxylation of indole-3-carboxylic acids. The decarboxylation can be achieved smoothly under K<sub>2</sub>CO<sub>3</sub>-catalyzed or acetonitrile-promoted basic conditions. It provided an efficient and simple method for the transformation of indole-3-carboxylic acids and the corresponding indoles were isolated with good to excellent yields. From the experimental facts, we put forward the possible reaction mechanism.</p> 2020-02-14 12:50:02 Decarboxylation indole-3-carboxylic acids indoles metal-free