Zhang, Lei Lin, Hai-Qing Li, Gui-Sheng Yue, Xi-Dian Dai, Sheng-Jun New sesquiterpenoid derivatives from <i>Solanum septemlobum</i> with cytotoxicities <div><p>Two new sesquiterpenoid derivatives, attributable to eudesmane-type (<b>1</b>–<b>2</b>, named septemlobin D and 11,12-<i>O</i>-isopropylidenesolajiangxin F), were isolated from the whole plant of <i>Solanum septemlobum</i>. Their structures were elucidated on the basis of integrated spectroscopic techniques, mainly HR-FAB-MS, 1D and 2D-NMR (<sup>1</sup>H–<sup>1</sup>H COSY, HMQC, HMBC and ROESY). <i>In vitro</i>, two sesquiterpenoid derivatives were found to show significant cytotoxicity against three cancer cell lines (P-388, HONE-1 and HT-29), and gave IC<sub>50</sub> values in the range of 3.0–7.3 μM.</p></div> cancer cell lines;roesy;ht;sesquiterpenoid derivatives;cosy;hmbc;Solanum septemlobum;IC 50 values;HONE;hmqc;New sesquiterpenoid derivatives 2015-10-08
    https://tandf.figshare.com/articles/journal_contribution/New_sesquiterpenoid_derivatives_from_i_Solanum_septemlobum_i_with_cytotoxicities/1308464
10.6084/m9.figshare.1308464.v4