Custódio, Luísa H. Engelen, Aschwin Pereira, Hugo Vizetto-Duarte, Catarina Barreira, Luísa Alberício, Fernando Varela, João Laukaityte, Simona João Rodrigues, Maria Rodríguez, Hortensia A comparative evaluation of biological activities and bioactive compounds of the seagrasses <i>Zostera marina</i> and <i>Zostera noltei</i> from southern Portugal <div><p>This work assessed the antioxidant potential, acetylcholinesterase (AChE) inhibition and the <i>in vitro</i> cytotoxic activity of extracts of the seagrasses <i>Zostera marina</i> and <i>Zostera noltei</i> collected from southern Portugal. The total phenolic contents (TPCs), the rosmarinic acid (RA) concentration (HPLC/DAD) and the fatty acid (FA) profile (GC/MS) are also described. <i>Z. marina</i> had the highest TPC, radical scavenging activity against DPPH radicals and copper chelating activity. <i>Z. noltei</i> had metal chelation capacity to copper and iron ions. None of the species was able to inhibit AChE. Both seagrasses had high levels of polyunsaturated FAs. <i>Z. marina</i> significantly and selectively reduced the viability of tumorous neuronal cells. <i>Z. noltei</i> was highly toxic for the three cell lines tested and was selective against hepatocarcinoma cells at the concentration of 100 μg/mL. RA was the main compound identified in <i>Z. marina</i>, but not in <i>Z. noltei</i>.</p></div> fa;concentration;acid;ra;ache;hplc;tpc;GC;compound;Portugal;dpph;copper chelating activity;Zostera noltei;metal chelation capacity;seagrasses Zostera marina 2015-07-20
    https://tandf.figshare.com/articles/journal_contribution/A_comparative_evaluation_of_biological_activities_and_bioactive_compounds_of_the_seagrasses_i_Zostera_marina_i_and_i_Zostera_noltei_i_from_southern_Portugal/1488634
10.6084/m9.figshare.1488634.v1