10.6084/m9.figshare.1488635.v1 Hai-Feng Wu Hai-Feng Wu Qiong-Yu Zou Qiong-Yu Zou Yu-Lian Tang Yu-Lian Tang Di-Zhao Chen Di-Zhao Chen A new labdane diterpene from the rhizomes of <i>Alpinia officinarum</i> Taylor & Francis Group 2015 hela acid kaempferol isopropyl compound method rhizome cytotoxic galangin spectroscopic ethanolic quercetin sesquiterpene ic Alpinia officinarum labdane diterpene HepG 2 cancer cell lines cadinane 2015-07-15 00:00:00 Journal contribution https://tandf.figshare.com/articles/journal_contribution/A_new_labdane_diterpene_from_the_rhizomes_of_i_Alpinia_officinarum_i_/1488635 <div><p>A new labdane diterpene, (<i>Z</i>)-12,14-labdadien-15(16)-olide-17-oic acid (<b>1</b>), and a new natural cadinane sesquiterpene, 4-isopropyl-6-methyl-1-naphthalenemethanol (<b>2</b>), were isolated from the ethanolic extract of the rhizomes of <i>Alpinia officinarum</i>, together with three other products, galangin (<b>3</b>), kaempferol (<b>4</b>) and quercetin (<b>5</b>). Their structures were elucidated by using extensive spectroscopic methods. Compounds <b>1</b> and <b>2</b> showed no remarkable cytotoxic activity against HeLa and HepG2 cancer cell lines with IC<sub>50</sub>>50 μg mL<sup>− 1</sup>.</p></div>