10.6084/m9.figshare.1488635.v1
Hai-Feng Wu
Hai-Feng
Wu
Qiong-Yu Zou
Qiong-Yu
Zou
Yu-Lian Tang
Yu-Lian
Tang
Di-Zhao Chen
Di-Zhao
Chen
A new labdane diterpene from the rhizomes of <i>Alpinia officinarum</i>
Taylor & Francis Group
2015
hela
acid
kaempferol
isopropyl
compound
method
rhizome
cytotoxic
galangin
spectroscopic
ethanolic
quercetin
sesquiterpene
ic
Alpinia officinarum
labdane diterpene
HepG 2 cancer cell lines
cadinane
2015-07-15 00:00:00
Journal contribution
https://tandf.figshare.com/articles/journal_contribution/A_new_labdane_diterpene_from_the_rhizomes_of_i_Alpinia_officinarum_i_/1488635
<div><p>A new labdane diterpene, (<i>Z</i>)-12,14-labdadien-15(16)-olide-17-oic acid (<b>1</b>), and a new natural cadinane sesquiterpene, 4-isopropyl-6-methyl-1-naphthalenemethanol (<b>2</b>), were isolated from the ethanolic extract of the rhizomes of <i>Alpinia officinarum</i>, together with three other products, galangin (<b>3</b>), kaempferol (<b>4</b>) and quercetin (<b>5</b>). Their structures were elucidated by using extensive spectroscopic methods. Compounds <b>1</b> and <b>2</b> showed no remarkable cytotoxic activity against HeLa and HepG2 cancer cell lines with IC<sub>50</sub>>50 μg mL<sup>− 1</sup>.</p></div>