10.6084/m9.figshare.1629346
Sarah-Jo Stimpson
Sarah-Jo
Stimpson
Erin C. Rebele
Erin
C. Rebele
Michael R. DeBaun
Michael
R. DeBaun
Common gynecological challenges in adolescents with sickle cell disease
Taylor & Francis Group
2016
Contraception
menstrual cycle
progesterone
sickle cell anemia
sickle cell disease
vaso-occlusive pain
menorrhagia
iron deficiency anemia
2016-01-05 14:53:06
Dataset
https://tandf.figshare.com/articles/dataset/Common_gynecological_challenges_in_adolescents_with_sickle_cell_disease/1629346
<p>Sickle cell anemia is one of the most common genetic blood disorders worldwide. Individuals with sickle cell disease (SCD) experience clinical manifestations such as chronic anemia, developmental delay, vaso-occlusive pain, acute chest syndrome, and neurological complications. Adolescent girls with SCD face unique gynecological challenges including delayed puberty marked by a later onset in menarche, vaso-occlusive pain associated with their menstrual cycle, and underdiagnosed abnormal uterine bleeding. This review focuses on these challenges with particular emphasis on delayed menarche and vaso-occlusive pain episodes associated with menstruation, in addition to the evaluation and initial management of heavy menstrual bleeding for adolescents with SCD. We highlight research opportunities in this neglected area to help enhance the comprehensive care model for this population.</p>