A. Gharad, Spruha N. Berad, Baliram A. Chavan, Snehal Synthesis of quinoline based [1,2,4]-dithiazolidines through sulfur-sulfur bond formation and their evaluation as anti-inflammatory and antibacterial agents <p>A series of [1,2,4]-dithiazolidines carrying the quinoline moiety has been synthesized. 2-Chloroquinolin-3-carbaldehyde reacted with various 4-arylthiosemicarbazides to form the corresponding 1-[(2-chloroquinolin-3-yl)methylene]-4-arylthiosemicarbazides. The synthesis of 3,5-(diarylimino)-4[(2-chloroquinolin-3-yl)methyleneamino]-[1,2,4]-dithiazolidines was achieved by the interaction of 1-[(2-chloroquinolin-3-yl)methylene]-4-arylthiosemicarbazides with <i>N</i>-aryl-<i>S</i>-chloroisothiocarbamoyl chlorides through S–S and C–N bond formations. The structures of newly synthesized compounds were confirmed on the basis of IR, <sup>1</sup>H & <sup>13</sup>C NMR and Mass spectral data. The title compounds were screened for their anti-inflammatory and antibacterial activities.</p> [1,2,4]-Dithiazolidine;2-Chloroquinolin-3-carbaldehyde; 4-arylthiosemicarbazides;N-aryl-S-chloroisothiocarbamoyl chloride;antibacterial activity;anti-inflammatory activity 2016-02-06
    https://tandf.figshare.com/articles/journal_contribution/Synthesis_of_quinoline_based_1_2_4_dithiazolidines_through_sulfur_sulfur_bond_formation_and_their_evaluation_as_anti_inflammatory_and_antibacterial_agents/2074456
10.6084/m9.figshare.2074456