Magnetic nanoparticles modified with quaternarized <i>N</i>-halamine based polymer and their antibacterial properties Xiaoqin Chen Bojian Hu Qian Xiang Chunyan Yong Zuliang Liu Xiaodong Xing 10.6084/m9.figshare.3407224 https://tandf.figshare.com/articles/journal_contribution/Magnetic_nanoparticles_modified_with_quaternarized_i_N_i_-halamine_based_polymer_and_their_antibacterial_properties/3407224 <p>We present a simple and facile approach for preparing antibacterial magnetic nanoparticles, which were modified with quaternarized <i>N</i>-halamine based cationic polymer (CPQN). The CPQN functionalized magnetic nanoparticles (MNPs-CPQN) were characterized by X-ray photoelectron spectra, Fourier transform infrared spectroscopy, transmission electron microscopy, scanning electron microscopy, and thermogravimetric analysis. Antibacterial properties were investigated with Gram positive bacteria <i>S. aureus</i> and Gram negative bacteria <i>E. coli</i>. Antibacterial assessment showed that the MNPs-CPQN could eliminate nearly 100% of <i>S. aureus</i> and 99.9% of <i>E. coli</i> (10<sup>7-8</sup> CFU/mg nanoparticles) in 5 min, while the bactericide rate of quaternized <i>N</i>-halamine precursor based cationic polymer coated magnetic nanoparticles (MNPs-CPQNP) were 99.6 and 95.2%, respectively. The prepared nanoparticles exhibited a good response to an external magnetic field and had a saturation magnetization of 36.6 emu g<sup>−1</sup>. On the basis of their excellent antibacterial properties and magnetic responsiveness, the MNPs-CPQN would be a promising antibacterial material for water disinfection.</p> 2016-05-31 11:26:36 Antibacterial magnetic nanoparticles cationic polymer N-halamine quaternary ammonium salts