10.6084/m9.figshare.3858963.v1
Yuan-Yuan Zhou
Yuan-Yuan
Zhou
Quan-Yu Liu
Quan-Yu
Liu
Bing-You Yang
Bing-You
Yang
Yan-Qiu Jiang
Yan-Qiu
Jiang
Yu-Xin Liu
Yu-Xin
Liu
Ying Wang
Ying
Wang
Shuang Guo
Shuang
Guo
Haixue Kuang
Haixue
Kuang
Two new cytotoxic glycosides isolated from the green walnut husks of <i>Juglans mandshurica</i> Maxim.
Taylor & Francis Group
2016
Juglans mandshurica
alcohol glycoside
phenolic glycoside
cytotoxic activity
2016-09-26 12:55:41
Journal contribution
https://tandf.figshare.com/articles/journal_contribution/Two_new_cytotoxic_glycosides_isolated_from_the_green_walnut_husks_of_i_Juglans_mandshurica_i_Maxim_/3858963
<p>Two new glycosides including an alcohol glycoside and a phenolic glycoside: hexyl-1-<i>O</i>-<i>α</i>-d-arabinofuranosyl-(1 → 6)-<i>β</i>-d-glucopyranoside (<b>1</b>), 4-hydroxypropiophenone-4-<i>O</i>-<i>β</i>-d-glucopyranosyl(1 → 6)-<i>β</i>-d-glucopyranoside(<b>2</b>), along with six known naphthalenyl glucosides (<b>3</b>–<b>8</b>) were isolated from green walnut husks of <i>Juglans mandshurica</i>, and their structures were elucidated on the basis of spectroscopic studies. All compounds were evaluated for their inhibitory effects on tumour cells (BGC-823, HepG-2, MCF-7). The results showed that new compounds <b>1</b> and <b>2</b> had superior inhibitory activity in comparison with other naphthalenyl glucosides.</p>