10.6084/m9.figshare.5303314
Niannian Yi
Niannian
Yi
Jinxia Li
Jinxia
Li
Hao Zhang
Hao
Zhang
Ruijia Wang
Ruijia
Wang
Jun Jiang
Jun
Jiang
Wei Deng
Wei
Deng
Zebing Zeng
Zebing
Zeng
Jiannan Xiang
Jiannan
Xiang
Synthesis of 3-acylated indoles through iron-catalyzed oxidative coupling of indoles with α-amino carbonyl compounds
Taylor & Francis Group
2017
3-Acylindoles
α-amino carbonyl compound
iron
oxidative coupling
2017-10-05 14:36:53
Journal contribution
https://tandf.figshare.com/articles/journal_contribution/Synthesis_of_3-acylated_indoles_via_iron-catalyzed_oxidative_coupling_of_indoles_with_-amino_carbonyl_compounds/5303314
<p>A novel iron-catalyzed oxidative coupling of indoles with α-amino carbonyl compounds has been developed. The transformation provides an attractive approach to the synthesis of 3-acylindoles, with the advantages of easily available starting materials and high functional group tolerance. Furthermore, control experiments imply that a radical process maybe involved in this reaction.</p>