Synthesis of 3-acylated indoles through iron-catalyzed oxidative coupling of indoles with α-amino carbonyl compounds Niannian Yi Jinxia Li Hao Zhang Ruijia Wang Jun Jiang Wei Deng Zebing Zeng Jiannan Xiang 10.6084/m9.figshare.5303314 https://tandf.figshare.com/articles/journal_contribution/Synthesis_of_3-acylated_indoles_via_iron-catalyzed_oxidative_coupling_of_indoles_with_-amino_carbonyl_compounds/5303314 <p>A novel iron-catalyzed oxidative coupling of indoles with α-amino carbonyl compounds has been developed. The transformation provides an attractive approach to the synthesis of 3-acylindoles, with the advantages of easily available starting materials and high functional group tolerance. Furthermore, control experiments imply that a radical process maybe involved in this reaction.</p> 2017-10-05 14:36:53 3-Acylindoles α-amino carbonyl compound iron oxidative coupling