%0 Journal Article %A Bukvički, Danka %A Novaković, Miroslav %A Ghani, Nurunajah Ab %A Marin, Petar D. %A Asakawa, Yoshinori %D 2017 %T Secondary metabolites from endemic species Iris adriatica Trinajstić ex Mitić (Iridaceae) %U https://tandf.figshare.com/articles/journal_contribution/Secondary_metabolites_from_endemic_species_i_Iris_adriatica_i_Trinajsti_ex_Miti_Iridaceae_/5592772 %R 10.6084/m9.figshare.5592772.v1 %2 https://tandf.figshare.com/ndownloader/files/9728836 %K Iris adriatica %K rhizome %K isoflavonoids %K 1D and 2D NMR %K HR-EI-MS %X

This manuscript describes the first detailed chemical investigation of endemic species Iris adriatica, including isolation and structure elucidation. Chemical analyses of the rhizome CH2Cl2/MeOH (2:1) extract revealed fourteen secondary metabolites, mainly isoflavonoids. Among isoflavonoids, two groups have been found: nigricin-type and tectorigenin-type. Dominant group of the isolated compounds has been nigricin-type isoflavones: nigricin, nigricin-4′-(1-O-β-D-glucopyranoside) and nigricin-4′-(1-O-β-D-glucopyranosyl (1–6)-β-D-glucopyranoside) with 2.5, 10 and 1% of the total extract, respectively. Irisxanthone – xanthone C-glucoside, β-sitosterol, benzophenone and one of its derivatives have also been found. Nigricin-type isoflavonoids and irisxanthone can be considered as possible chemotaxonomic markers for I. adriatica. 5,3′,5′-Trimethoxy-6,7-methylenedioxyisoflavone-4′-(1-O-β-D-glucopyranoside) and benzophenone have been isolated from Iris species for the first time.

Left-hand image of Iris adriatica (Adriatic potato) with redditsh purple flowers © Miroslav Mitić. All Rights Reserved.

%I Taylor & Francis