Expeditious synthesis of 9-allenylpurines <i>via</i> cesium carbonate catalyzed isomerization of 9-alkynylpurines YuMingwu LiuXiguang JiangQingsong DuHongguang 2018 <p>An expeditious and convenient method to synthesize 9-allenylpurines <i>via</i> cesium carbonate catalyzed isomerization of 9-alkynylpurines has been successfully developed. The reactions proceeded rapidly under the base conditions and formed the desired products in good to excellent yields. The method was suitable with a broad substrate scope and proceeded well even on a multgram-scale. The obtained 9-allenylpurines were successfully applied to prepare various potential bioactive 9-acyclic nucleosides with high regioselectivity promoted by AgNO<sub>3</sub>.</p>