Chen, Junmin Zhang, Kuo Zhao, Yongli Pu, Shouzhi Primary sulfonamide as a coupling partner: Copper(I)-catalyzed regioselective cross-coupling of 2-nitro benzenesulfonamides with thiol through the cleavage of Ar–SO<sub>2</sub>NH<sub>2</sub> bonds <p>In this article, we have presented a novel and efficient method for the direct synthesis of unsymmetrical sulfides through the copper(I)-catalyzed cross-coupling of 2-nitro benzenesulfonamides with thiols in the presence of catalytic amount of CuI in DMF as solvent at 100 °C. In addition, the products were obtained in high to excellent yields. More importantly, the novel system showed the primary 2-nitro benzenesulfonamides as a new coupling partner and regioselectively promoted C–S bond-forming transformations through the cleavage of Ar–SO<sub>2</sub>NH<sub>2</sub> bonds.</p> Copper(I)-catalyzed;cross-coupling;regioselective;sulfonamide;thiol 2018-05-22
    https://tandf.figshare.com/articles/journal_contribution/Primary_sulfonamide_as_a_coupling_partner_Copper_I_-catalyzed_regioselective_cross-coupling_of_2-nitro_benzenesulfonamides_with_thiol_through_the_cleavage_of_Ar_SO_sub_2_sub_NH_sub_2_sub_bonds/6308660
10.6084/m9.figshare.6308660.v1