Piptolinic acids F–J, five new lanostane-type triterpenoids from <i>Piptoporus betulinus</i> KhalilovQosimjon LiLiya LiuYushuang TohtahonZeynep ChenXiaoyu AisaHaji Akber YuanTao 2019 <p>Five new lanostane-type triterpenoids, named piptolinic acids F − J (<b>1</b>–<b>5</b>), as well as seven known analogues (<b>6</b>–<b>12</b>), were isolated from methanolic extract of the fruiting bodies of <i>Piptoporus betulinus</i>. Compounds <b>1</b>–<b>4</b> were 24-methyl-lanostane triterpenoids, while compound <b>5</b> was a 3,4-<i>seco</i>-lanostane derivative. Their structures were established on the basis of extensive spectroscopic analysis (1D, 2D NMR, and HRESIMS). Cytotoxicity evaluation indicated that compound <b>6</b> exhibited moderate cytotoxic activity against human melanoma cell line A-375 (IC<sub>50</sub> = 42.8 μM) and human renal carcinoma cell line 786-O (IC<sub>50</sub> = 56.5 μM).</p>