10.6084/m9.figshare.7418396.v1
Miroslav Novakovic
Miroslav
Novakovic
Iris Djordjevic
Iris
Djordjevic
Nina Todorovic
Nina
Todorovic
Snezana Trifunovic
Snezana
Trifunovic
Boban Andjelkovic
Boban
Andjelkovic
Boris Mandic
Boris
Mandic
Milka Jadranin
Milka
Jadranin
Ivan Vuckovic
Ivan
Vuckovic
Vlatka Vajs
Vlatka
Vajs
Slobodan Milosavljevic
Slobodan
Milosavljevic
Vele Tesevic
Vele
Tesevic
New aurone epoxide and auronolignan from the heartwood of <i>Cotinus coggygria</i> Scop
Taylor & Francis Group
2018
Cotinus coggygria Scop
flavonoids
cotinignan A
semipreparative HPLC
NMR
2018-12-04 23:00:49
Journal contribution
https://tandf.figshare.com/articles/journal_contribution/New_aurone_epoxide_and_auronolignan_from_the_heartwood_of_i_Cotinus_coggygria_i_Scop/7418396
<p>New aurone epoxide, 2,10-oxy-10-methoxysulfuretin (<b>14</b>), and new auronolignan (<b>15</b>), named cotinignan A, were isolated by silica gel column and semipreparative HPLC chromatography from the methylene chloride/methanol extract of <i>Cotinus coggygria</i> Scop. heartwood. In addition, thirteen known secondary metabolites namely sulfuretin, 2,3-<i>trans</i>-fustin, fisetin, butin, butein, taxifolin, eriodictyol, 3',5,5',7–tetrahydroxyflavanone, 3',4',7-trihydroxyflavone, 3-<i>O</i>-methyl-2,3-<i>trans</i>-fustin, 3-<i>O</i>-galloyl-2,3-<i>trans</i>-fustin, <i>β</i>-resorcylic acid and 3-<i>O</i>-<i>β</i>-sitosterol glucoside were isolated as well. Their structures were elucidated by 1D and 2D NMR, HR-ESI-MS, IR and UV. Ten out of eleven isolated flavonoids possess 7, 3' and 4' hydroxy groups. These structural features could be considered as chemotaxonomic characteristic of flavonoids from <i>C. coggygria</i>. Cotinignan A (<b>15</b>) represents new subclass of secondary metabolites - auronolignans.</p> <p></p>