Huang, Lei Peng, Tong Li, Yu He, Yunyun Wang, Li Zhang, Shiyan Sun, Yiran Chen, Fang Tang, Lin A new phenolic glycoside from the <i>Idesia polycarpa</i> Maxim. leaves <p>Phytochemical investigation on the ethyl acetate extract of <i>Idesia polycarpa</i> Maxim. Leaves led to the isolation of four phenolic glycoside isomers (<b>1–4</b>). Compound <b>2</b> appeared to be new reported phenolic glycoside, while compound <b>1</b> was the first time isolated from the titled species. Their structures were established by IR, UV, HRESI-MS and 1D and 2D NMR spectroscopies analysis and comparison of spectral data with previously reported data. The compounds <b>3</b> and <b>4</b> showed stronger activity of scavenging the DPPH free radical than the other two compounds, while the compounds <b>1</b> and <b>2</b> showed a significant activity of scavenging the ABTS free radical. Compounds <b>2</b> and <b>4</b> exhibited stronger cytotoxicity against HepG2 cell lines compared to compounds <b>1</b> and <b>3</b>. Moreover, compound <b>3</b> presented the highest cytotoxicity against MCF cell lines with IC<sub>50</sub> value of 37.17 ± 0.26 μg/mL than compounds <b>1</b>, <b>2</b> and <b>4</b>.</p> Idesia polycarpa Maxim.;phenolic glycoside isomers;cytotoxicity;antioxidant 2018-12-09
    https://tandf.figshare.com/articles/journal_contribution/A_new_phenolic_glycoside_from_the_i_Idesia_polycarpa_i_Maxim_leaves/7441295
10.6084/m9.figshare.7441295.v1