10.6084/m9.figshare.7454081.v1
Adil Omar
Adil
Omar
Keyume Ablajan
Keyume
Ablajan
Efficient one-pot catalyst-free synthesis of novel coumarin- spiro[indoline-3,4'-pyran] conjugates via three-component domino reaction in aqueous medium
Taylor & Francis Group
2018
Coumarins
spiro-indoline
pyran
one-pot synthesis
catalyst-free
2018-12-12 06:44:13
Journal contribution
https://tandf.figshare.com/articles/journal_contribution/Efficient_one-pot_catalyst-free_synthesis_of_novel_coumarin-_spiro_indoline-3_4_-pyran_conjugates_via_three-component_domino_reaction_in_aqueous_medium/7454081
<p>A simple, efficient, eco-friendly and catalyst-free procedure was developed for the construction of novel coumarin-spiro[indoline-3,4'-pyran] conjugates via three-component reactions of various synthetic beta-ketoesters with isatins and malononitrile in aqueous medium. In addition to operational simplicity and absence of tedious separation procedures, being catalyst–free is the prominent advantage of this method.</p>