10.6084/m9.figshare.7638236.v1 Radica S. Živković Zarić Radica S. Živković Zarić Ana V. Pejčić Ana V. Pejčić Slobodan M. Janković Slobodan M. Janković Marina J. Kostić Marina J. Kostić Miloš N. Milosavljević Miloš N. Milosavljević Marko J. Milosavljević Marko J. Milosavljević Valentina D. Opančina Valentina D. Opančina Antimicrobial treatment of <i>Kocuria kristinae</i> invasive infections: Systematic review Taylor & Francis Group 2019 Antibiotic treatment Invasive infections Kocuria kristinae Systematic review 2019-01-28 18:12:16 Journal contribution https://tandf.figshare.com/articles/journal_contribution/Antimicrobial_treatment_of_i_Kocuria_kristinae_i_invasive_infections_Systematic_review/7638236 <p>Objective of this systematic review was to establish whether and what invasive infections in humans were caused by <i>Kocuria kristinae</i>, and to evaluate outcomes of administered antibiotic treatment. MEDLINE, EBSCO, SCOPUS, SCINDEKS and GOOGLE SCHOLAR were systematically searched for primary case reports or case series describing invasive infections with <i>K. kristinae</i>. <i>K. kristinae</i> is a pathogen microorganism that could cause invasive infections of various tissues in patients of any age. Majority of the patients had <i>K. kristinae</i> isolated from blood. It was also found in peritoneal fluid, pus, sputum, synovial fluid, bile, fluid from abdominal abscess, throat swab, urine catheter tip and mid-stream urine. Antibiotic treatment was almost universally effective, with only one death reported. Susceptibility was highest to vancomycin, linezolid, rifampicin, teicoplanin, tigecycline, cefotaxime, ampicillin/sulbactam, minocycline and meropenem. Initial treatment of <i>Kocuria kristinae</i> infections should involve parenteral vancomycin in combination with some other antibiotic to which it is susceptible.</p>