%0 Journal Article %A Qi, Shizhou %A Yang, Yiren %A Xian, Xiaoyan %A Li, Xianzhe %A Gao, Huiyuan %D 2019 %T A new sesquiterpenoid glycoside from Saussurea involucrata %U https://tandf.figshare.com/articles/journal_contribution/A_new_sesquiterpenoid_glycoside_from_i_Saussurea_involucrata_i_/7717850 %R 10.6084/m9.figshare.7717850.v1 %2 https://tandf.figshare.com/ndownloader/files/14366504 %K antioxidant %K anti-inflammatory %K Saussurea involucrata %K sesquiterpenoid glycoside %X

Saussurea involucrata, known for the abundant bioactive components, is a precious traditional Chinese medicine. In this study, a novel guaiane sesquiterpenoid glycoside named (1R, 5R, 6R, 7R, 8S, 11S)-11, 13-dihydrodehydrocostuslactone-8-O-6'-2''(E)-butenoyl-β-D-glucopyranoside (1), together with seven known compounds (28) were isolated from the dried aerial part of S. involucrata. Their structures were elucidated by spectroscopic and physico-chemical analyses. The antioxidant and anti-inflammatory activities of compound 1 were investigated. And compound 1 showed weak radical scavenging activity and low inhibitory activity on nitric oxide (NO) production.

%I Taylor & Francis