One-pot three-component reaction of arylglyoxals with acetylthiourea and Meldrum’s acid or barbituric acid for synthesis of new 2-acetamido-4-arylthiazol-5-yl derivatives
Farzaneh Alizadeh-Bami
Hossein Mehrabi
Reza Ranjbar-Karimi
10.6084/m9.figshare.7959236.v1
https://tandf.figshare.com/articles/journal_contribution/One-pot_three-component_reaction_of_arylglyoxals_with_acetylthiourea_and_Meldrum_s_acid_or_barbituric_acid_for_synthesis_of_new_2-acetamido-4-arylthiazol-5-yl_derivatives/7959236
<p>An efficient method for the synthesis of 2-acetamido-4-arylthiazol-5-yl derivatives <i>via</i> a novel one-pot three-component reaction of arylglyoxals, 1,3-dicarbonyl compounds such as Meldrum’s acid or barbituric acid, and acetylthiourea in ethanol is reported.</p>
2019-04-05 15:01:08
Meldrum’s acid
barbituric acid
acetylthiourea
arylglyoxal
2-acetamido-4-arylthiazol-5-yl
one-pot three-component reaction