10.6084/m9.figshare.7998794.v1
Shuai Lin
Shuai
Lin
Rong-Hua Liu
Rong-Hua
Liu
Guang-Qiang Ma
Guang-Qiang
Ma
Dan-Yi Mei
Dan-Yi
Mei
Feng Shao
Feng
Shao
Lan-Ying Chen
Lan-Ying
Chen
Two new compounds from the heartwood of <i>Dalbergia melanoxylon</i>
Taylor & Francis Group
2019
Neoflavonoid
benzofuran
Dalbergia melanoxylon
antimicrobial activity
2019-04-16 12:19:29
Journal contribution
https://tandf.figshare.com/articles/journal_contribution/Two_new_compounds_from_the_heartwood_of_i_Dalbergia_melanoxylon_i_/7998794
<p>A new neoflavonoid, named <i>S</i>(+)-3′-hydroxy-4′,2,4,5-tetramethoxydalbergiquinol (<b>1</b>), and a new benzofuran, named (2<i>S</i>,3<i>S</i>)-5-hydroxy-6-methoxy-3-methyl-2-(4′-hydroxyphenyl)-2,3dihydrobenzofuran <b>(4)</b>, together with two known neoflavonoids, were isolated from the heartwood of <i>Dalbergia melanoxylon.</i> Their structures were elucidated by a combination of spectroscopic methods and comparison with the literature. Compounds <b>1–4</b> were evaluated for inhibitory activity against <i>Staphylococcus aureus</i> ATCC 25923, <i>Escherichia coli</i> ATCC 6538, <i>Salmonella enteri</i> CMCC 50041 and <i>Candida albicans</i> ATCC 289065, which all exhibited inactive or weak activity.</p>