Antifungal activity of Mongolian medicinal plant extracts GiordaniCristiano SimonettiGiovanna NatsagdorjDamdinsuren ChoijamtsGotov GhirgaFrancesca CalcaterraAndrea QuaglioDeborah De AngelisGiulia TonioloChiara PasquaGabriella 2019 <p>The <i>in vitro</i> antifungal activity of extracts obtained from 14 medicinal plants of the mongolian flora were investigated by measuring their minimal inhibitory concentration (MIC) against fungi cause of cutaneous diseases such as <i>Candida</i> species, dermatophytes and <i>Malassezia furfur</i>. Among the species examined, <i>Stellaria dichotoma</i> L., <i>Scutellaria scordifolia</i> L. <i>Aquilegia sibirica</i> Fisch. Et Schrenk. and <i>Hyoscyamus niger</i> L. extracts demonstrated antifungal activity against all studied fungi. In particular, <i>S. scordifolia</i> L. methanol extract, obtained at room temperature, showed the best activity against <i>Candida</i> spp., <i>Malassezia furfur</i> and dermatophytes with GMMIC<sub>50</sub> values of 22 µg/mL, 64 µg/mL and 32 µg/mL, respectively. The flavones, luteolin and apigenin, identified in <i>S. scordifolia</i> extracts, and rutin identified in <i>S. dichotoma</i> and <i>Hyoscyamus niger</i> L. extracts, could be responsible of the observed antifungal activity.</p> <p></p>