Bujuq, Nader Al Strategies for introducing sulfur atom in a sugar ring: synthesis of 5-thioaldopyranoses and their NMR data <p>Thiosugars containing a sulfur atom as heteroatom in the sugar ring are highly interesting. In particular, 5-thioaldopyranoses have attracted considerable attention because they exhibit biologically important properties as the substrates for glycosidases also can be developed as potential therapeutical agents, such as antineoplastic, anti-diabetic, antiviral, and antithrombotic agents. In this review, we describe and discuss the advances in synthetic strategies for the preparation of 5-thioaldopyranoses (5-thio-d-hexoses, 5-thio-l-hexoses, 5-thio-d-pentoses and 5-thio-l-pentoses), as well as their spectroscopic NMR data as known to date. The study aims to give readers an easy understanding of thiosugars chemistry and provide a useful guide for carbohydrate chemists.</p> 5-thiosugars;5-thioaldopyranoses;5-thioaldohexopyranoses;5-thioaldopentopyranoses;episulfides 2019-05-29
    https://tandf.figshare.com/articles/journal_contribution/Strategies_for_introducing_sulfur_atom_in_a_sugar_ring_synthesis_of_5-thioaldopyranoses_and_their_NMR_data/8197628
10.6084/m9.figshare.8197628.v1