Design, synthesis and herbicidal activity of novel cyclic phosphonates with diaryl ethers containing pyrimidine Shasha Zhang Xinjuan Guo Yuan Zhou Yalan Yang Hao Peng Hongwu He 10.6084/m9.figshare.8332463.v1 https://tandf.figshare.com/articles/journal_contribution/Design_synthesis_and_herbicidal_activity_of_novel_cyclic_phosphonates_with_diaryl_ethers_containing_pyrimidine/8332463 <p>Thirteen novel cyclic phosphates were rationally designed and synthesized by introducing diary ethers containing pyrimidine. All the target compounds were characterized by <sup>1</sup>H, <sup>13</sup>C, <sup>31</sup>P NMR and HRMS. The test of herbicidal activity indicated that most of the compounds showed good herbicidal activities against <i>Amaranthus retroflexus</i>. The compounds <b>IA-2</b> (1-(5,5-dimethyl-2-oxido-1,3,2-dioxaphosphinan-2-yl)propyl-2-((4,6-dimethoxypyrimidin-2-yl)oxy)benzoate) and <b>IA-3</b> ((5,5-dimethyl-2-oxido-1,3,2-dioxaphosphinan-2-yl)(phenyl)methyl<b>-</b>2-((4,6-dimethoxypyrimidin-2-yl)oxy)benzoate) exhibited remarkable post-emergency herbicidal activity against the tested monocotyledonous weed at the dosage of 112.5 g ai/ha.</p> 2019-06-27 09:52:03 Synthesis herbicidal activity diary ether heterocyclic phosphonate