A new aliphatic ester of hydroxysalicylic acid from fermented Carica papaya L. preparation with a potential hair growth stimulating activity

<p>An aliphatic ester of hydroxysalicylic acid (<b>6</b>), reported for the first time from a natural source in addition to five known compounds were isolated from the fermented <i>Carica papaya</i> L. preparation, a commercialized functional food. The known compounds were identified as 5-hydroxymethylfurfuraldehyde (<b>1</b>), <i>trans</i>-caffeic acid (<b>2</b>), butyl 4-hydroxybenzoate (butylparaben) (<b>3</b>), lycopene (<b>4</b>), benzyl isothiocyanate (<b>5</b>). Compounds <b>1</b> and <b>3</b> were reported for the first time from Papaya fruits through this study. The new compound showed a moderate antioxidant activity and a potent hair growth stimulating activity <i>in vitro</i>.</p>