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A new glucopyranoside from the leaves of Microsorium fortunei

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journal contribution
posted on 2020-02-25, 07:12 authored by Mengqi Yan, Qin Luo, Xianli Zhou, Qinghu Mo, Caifeng Peng, Xiaoya Xian, Xiao Huang, Xinping Yang, Xu Chen, Chengqin Liang

A new compound, 2-hydroxy-4-[3’,5’-dihydroxyhexyl]phenyl-β-D-glucopyranoside (1), together with five known compounds (26), were isolated from the leaves of Microsorium fortunei. Their structures were determined by spectroscopic techniques, especially 2D NMR and MS data analyses. All of these compounds are phenolic glycosides and were isolated from this plant for the first time. In addition, compound 1 showed moderate inhibitory activity against α-glucosidase with IC50 value at 0.111 ± 0.061 mg/mL.

Funding

This work was supported by the [National Natural Science Foundation of China] under Grant [No. 31560100; No. 81860621]; [Natural Science Fund of Guangxi Province] under Grant [No. 2017GXNSFAA198242; No. 2018GXNSFBA281032; No. 2018GXNSFAA281102; No. 2018GXNSFBA281079], and [State Key Laboratory for Chemistry and Molecular Engineering of Medicinal Resources] (Guangxi Normal University) under Grant [No. CHEMR2017-B15].

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