lsyc_a_1768406_sm3335.docx (2.13 MB)
A novel approach for the synthesis of functionalized hydroxylamino derivative of dihydroquinazolinones
journal contribution
posted on 2020-05-23, 16:58 authored by Chikkanti Jaganmohan, Vinay Kumar K. P., Venkateshwarlu R., Sandeep Mohanty, Jaydeep Kumar, Venkateswara Rao B., Akula Raghunadh, Krishnaji TadiparthiA new metal-free and modular approach for the synthesis of various functionalized dihydroquinazolinones has been developed from isatoic anhydride, amines, 4-chloro-N-hydroxybenzimidoylchloride to yield up to 71%. The reaction has been screened in various bases, solvents at different temperatures. The substrate scope of the reaction has been studied with various amines and the possible reaction mechanism for this reaction has also been proposed.