Taylor & Francis Group
Browse
gnpl_a_1046380_sm1320.pdf (359.45 kB)

Biofunctional properties of Eruca sativa Miller (rocket salad) hydroalcoholic extract

Download (0 kB)
journal contribution
posted on 2015-07-07, 00:00 authored by Khushbakht Sultan, Muhammad Zakir, Haroon Khan, Abdur Rauf, Noor Ul Akber, Murad Ali Khan

Eruca sativa Miller is a worldwide common alimentary plant (rocket leaves). The aim of this study was to correlate the potential in vitro scavenging activity of the E. sativa hydroalcoholic extract (HAE) with its in vivo hypoglycaemic effect. In DDPH free radical (DFR) and ferric-reducing antioxidant power assays, HAE in a concentration dependent manner (25–100 μg/mL) displayed a strong scavenging activity with maximum effect of 88% and 75% at 100 μg/mL, respectively. Daily administration of HAE (50 mg/kg; p.o.) in the in vivo model of alloxan-induced diabetic rabbits for 28 days showed significant reduction in glycaemia, also supported by recovery of body weight. In conclusion, our results give preliminary information on the potential use of this plant as a nutraceutical, useful to control and/or prevent a hyperglycaemic status.

History

Usage metrics

    Natural Product Research

    Licence

    Exports

    RefWorks
    BibTeX
    Ref. manager
    Endnote
    DataCite
    NLM
    DC