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Chemical constituents from Piper wallichii

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journal contribution
posted on 27.07.2015 by Yan-Ni Shi, Lian Yang, Jin-Hua Zhao, Yi-Ming Shi, Yan Qu, Hong-Tao Zhu, Dong Wang, Chong-Ren Yang, Xing-Cong Li, Min Xu, Ying-Jun Zhang

Fifteen known compounds including four triterpenoids (14), one sterol (5), one diketopiperazine alkaloid (6) and nine phenolics (715) were isolated from the stems of Piper wallichii. Their structures were elucidated by means of spectroscopic analysis, and acidic hydrolysis in case of the 2-oxo-3β,19α,23-trihydroxyurs-12-en-28-oic acid β-D-glucopyranosyl ester (1). The structure of compound 1 was fully assigned by 1D and 2D NMR experiments for the first time. All isolates were tested for their antibacterial, antifungal, anti-inflammatory and antiplatelet aggregation bioactivities.