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Concise synthesis of substituted meridianins

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Version 3 2021-02-05, 14:50
Version 2 2015-10-26, 03:26
Version 1 2015-10-26, 03:26
journal contribution
posted on 2015-10-26, 03:26 authored by Jenifer T.A. Vijay, Nandeesh K. Nagalingaiah, Sandhya C. Nagarakere, G.P. Suresha, Rangappa S. Kanchugarakoppal, Mantelingu Kempegowda

A mild and versatile method for the efficient construction of heterocyclic framework of meridianins from simple precursors has been devised. The strategy involves the assembly of the pyrimidine ring utilizing the nucleophilicitiy of monothio-1,3-diketone formed by thioacylation at the C-3 in the indole ring.

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