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Coordination-induced assembly of two coordination polymers: crystal structures and anticancer activity on nasopharyngeal carcinoma

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posted on 2020-04-29, 08:26 authored by Jing-Bo Zhai, Jie Zhou, Bo Zhang, Xue Wang

Two new coordination polymers [Y2(BPTC)(AcO)2(DMA)2] (1, DMA = N,N-dimethylacetamide) and [Ba2(BPTC)(H2O)5] (2) were constructed using different metal salts and 3,3′,5,5′‑biphenyltetracarboxylic acid (H4BPTC) as building blocks. The resulted coordination polymers were characterized by element analysis and single crystal X-ray crystallography. Furthermore, the in vitro anticancer activity of complexes 1 and 2 were studied via the CCK-8 (cell Counting Kit-8 assay) and Annexin V-FITC/PI double staining assay.

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