lsyc_a_1022660_sm3686.pdf (127.06 kB)
Copper-Catalyzed Synthesis of Valuable Heterocyclic Compounds Using a Tandem Oxidation Process Approach
Version 2 2015-05-05, 18:53
Version 1 2015-05-05, 18:53
journal contribution
posted on 2015-05-05, 18:53 authored by Vineet Jeena, Siphamandla Sithebe, Ross S. RobinsonThe synthesis of quinoxalines via a tandem oxidation process using a copper acetate monohydrate/2,2,6,6-tetramethylpiperidine N-oxyl (TEMPO) oxidative system has been described. Using this approach, a series of quinoxaline derivatives were formed in good yields within short reaction times under microwave irradiation. The oxidative system was also extended to the selective synthesis of dihydropyrazines and pyrazines.