gnpl_a_1557170_sm6167.pdf (1.14 MB)
Coumarin-pi, a new antioxidant coumarin derivative from Paxillus involutus
journal contribution
posted on 2019-01-12, 12:21 authored by Jin-Xiu Zhang, Jian-Hua Lv, Li-Qiang Zhao, Xiao-Xi Shui, Jun Zhang, Li-An WangChemical investigation of Paxillus involutus lead to the isolation of a new coumarin derivative coumarin-pi (1), and three known compounds (2-4). The structure of the new compound was elucidated by interpretation of 1D and 2D NMR data. Compound 1 possesses a rare benzofuranylcoumarin skeleton. The isolated compounds were evaluated for antioxidant activities and coumarin-pi (1) exhibited significant activity with IC50 value of 16.3 μg/mL.