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DPT-Mediated Synthesis of 2-Aminoimidazolidin-4-ones from Thioureas Tethered to Amides

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posted on 29.05.2014 by Sukumar Bepary, In Kwon Youn, Hee-Jong Lim, Ge Hyeong Lee

2-Aminoimidazolidin-4-ones have been synthesized by using di-2-pyridyl thiocarbonate (DPT), taking the thioureas tethered to amides as the starting materials. Both the primary amides and secondary amides have been subjected to this cyclization method and in general this simple and convenient method was found to ensure good to excellent yields (81–99%).

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