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Direct access to α,α′-diarylated ketones through N-heterocyclic carbene-catalyzed 1,6-addition of aromatic aldehydes to para-quinone methides

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Version 2 2017-03-30, 14:47
Version 1 2017-01-27, 14:46
journal contribution
posted on 2017-03-30, 14:47 authored by Guifu Zhang, Longxiang Jiang, Wenjuan Shi, Meiling Zhou, Fenghao Qiu, Shaofa Sun, Jian Wang, Haibing Guo

N-Heterocyclic carbene-catalyzed 1,6-addition of aromatic aldehydes to para-quinone methides has been developed. This method could efficiently furnish α,α′-diarylated ketones with good to high yields, which contain various functional groups.

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