Efficient synthesis and anti-bovine viral diarrhea virus evaluation of 5-(aryldiazo)salicylaldehyde thiosemicarbazone derivatives

Abbas, Samir Y.; Basyouni, Wahid M.; El-Bayouki, Khairy A. M.; Dawood, Reham M.; Abdelhafez, Tawfeek H.; Elawady, Mostafa K.

doi:10.6084/m9.figshare.8343410.v2

lsyc_a_1626893_sm0524.pdf (23.86 MB)

Efficient synthesis and anti-bovine viral diarrhea virus evaluation of 5-(aryldiazo)salicylaldehyde thiosemicarbazone derivatives

Version 2 2019-10-08, 05:34

Version 1 2019-06-28, 13:05

journal contribution

posted on 2019-10-08, 05:34 authored by Samir Y. Abbas, Wahid M. Basyouni, Khairy A. M. El-Bayouki, Reham M. Dawood, Tawfeek H. Abdelhafez, Mostafa K. Elawady

An efficient procedure for the synthesis of 5-(aryldiazo)salicylaldehyde thiosemicarbazone derivatives 1-25 was achieved via the condensation of 5-(aryldiazo)salicylaldehyde derivatives I–V with N-(4)-substituted thiosemicarbazide derivatives. Antiviral activity of the synthesized compounds was carried out. From the obtained results, it was noticed that compound 11 has a strong antiviral activity.