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Facile one-pot synthesis of new [1,2,4]triazolo[1,5-a]pyridine derivatives by ultrasonic irradiation

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posted on 05.10.2017 by Lazhar Zribi, Fathi Zribi, José Marco-Contelles, Fakher Chabchoub, Lhassane Ismaili

Herein, we report an ultrasonic promoted facile and convenient “one-pot” procedure for the synthesis of new [1,2,4]triazolo[1,5-a]pyridine derivatives 3, 4 and 5, using Amberlite IRA-400, in short reaction times and high yields and its comparison with classical reaction conditions. The structures of new compounds were assigned with the help of analytical 1H, 13C NMR, and mass spectral studies.

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This work was supported by Regional Council of Franche-Comte [Grant Numbers 2016YC-04540, 04560].

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