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Hybrid crystal NH3(CH2)4NH3SiF6 as an efficient catalyst for the synthesis of benzoxazoles, benzimidazoles and benzothiazoles under solvent-free conditions

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posted on 21.10.2016 by Zakaria Benzekri, Houda Serrar, Sara Sibous, Said Boukhris, Ali Ouasri, Ali Rhandour, Abdelaziz Souizi

An easy synthetic protocol for the synthesis of biologically active benzimidazole, benzothiazole and benzoxazole derivatives has been demonstrated using a hybrid crystal NH3(CH2)4NH3SiF6 as a mild and efficient heterogeneous catalyst. Short reaction times, solvent-free conditions, good to excellent yields, easy reusability and use of an eco-friendly catalyst are some of the significant attributes of the present method.

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