Integrated extraction and purification of total bioactive flavonoids from <i>Toona sinensis</i> leaves

<p>An integrated procedure was developed to extract and purify total flavonoids from <i>Toona sinensis</i> leaves for the first time, in which pressurized liquid extraction was performed in tandem with HPD100 macroporous resin column. Consequently, the total flavonoids can be extracted using 10% EtOH, and the recovery and purity of total flavonoids was 71.05% and 66.60%. Moreover, products of high quality were obtained in an environmentally friendly process with lower consumption of time and solvent. The results demonstrated that the integrated extraction-adsorption procedure was an efficient process for the preparation of total bioactive flavonoids from <i>Toona sinensis</i> leaves.</p>