Metal-free oxidation of secondary benzylic alcohols using aqueous TBHP

Wu, Jianglong; Liu, Yan; Ma, Xiaowei; Liu, Ping; Gu, Chengzhi; Dai, Bin

doi:10.6084/m9.figshare.3979134.v2

lsyc_a_1223307_sm6266.docx (19.47 MB)

Metal-free oxidation of secondary benzylic alcohols using aqueous TBHP

Version 2 2016-10-14, 15:10

Version 1 2016-10-03, 16:36

journal contribution

posted on 2016-10-14, 15:10 authored by Jianglong Wu, Yan Liu, Xiaowei Ma, Ping Liu, Chengzhi Gu, Bin Dai

We report a simple, yet efficient metal-free oxidation of secondary benzylic alcohols in the presence of t-butyl hydroperoxide (70% TBHP) with high yields of up to 98%. This type of reaction can be carried out using a wide variety of substrates, requires no other organic solvent, and proves to be tolerant toward a variety of different functional groups.