Microwave-assisted synthesis and crystal structure of some novel 1,2,4-oxadiazol-5-ylmethyl-1,2,3-triazoles

2017-03-23T13:45:26Z (GMT) by Yaşar Dürüst Hamza Karakuş
<p>Microwave-assisted 1,3-dipolar cycloaddition of 5-azidomethyl 3-aryl-substituted 1,2,4-oxadiazoles to electron-deficient alkyne; phenyl propiolic acid affords a series of 1,2,3-triazole derivatives carrying 3-<i>p</i>-substitutedphenyl-1,2,4-oxadiazolyl methyl unit. The structures of all the cycloadducts were elucidated by IR, NMR (<sup>1</sup>H, <sup>13</sup>C, 2D), MASS (low and high resolution) spectra, X-ray diffraction data, and physical characteristics (melting points and <i>R</i><sub>f</sub> values).</p>