NaOH/Et<sub>3</sub>N-Promoted Stereoselective One-Pot Synthesis of <i>α</i>-Diazo Oxime Ethers via Diazo Transfer Reaction

<div><p></p><p>For the first time, we have observed a combined effect of two bases NaOH/Et<sub>3</sub>N to promote the diazo transfer reaction of β-oximino esters. This unusual synergistic effect has been employed to obtain <i>α</i>-diazo oxime ethers directly from <i>β-</i>keto esters by one-pot process. This method is simple and cost-effective and the reagents are readily available.</p></div>