gnpl_a_1527836_sm6783.pdf (2.07 MB)
Narciclasine-4-O-β-D-xylopyranoside, a new narciclasine glycoside from Zephyranthes minuta
journal contribution
posted on 2019-01-12, 09:24 authored by Deepali Katoch, Dharmesh Kumar, Yogendra S Padwad, Bikram Singh, Upendra SharmaA new narciclasine glycoside, narciclasine-4-O-β-D-xylopyranoside (1) was characterised along with four known alkaloids pancratistatin (2), 1-O-(3-hydroxybutyryl) pancratistatin (3), vittatine (4), 9-O-demethylgalanthine (5) from Zephyranthes minuta. Their structures were established on the basis of spectroscopic data analysis. The in vitro cytotoxic study of extract, fractions and isolated compounds against two human cancer cell lines (KB and SiHa) indicated the potential activity of extract and n-butanol fraction due to presence of active alkaloids pancratistatin, 1-O-(3-hydroxybutyryl) pancratistatin, lycorine and haemanthamine.