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One new xanthenone from the marine-derived fungus Aspergillus versicolor MF160003

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journal contribution
posted on 2019-04-22, 16:23 authored by Zhijun Song, Jieyu Gao, Jiansen Hu, Hongtao He, Pei Huang, Lixin Zhang, Fuhang Song

A new xanthenone derivative, 3-hydroxy pinselin (1), together with five known analogues (2–6) were isolated from the marine-derived fungus Aspergillus versicolor MF160003. Their structures were identified by extensive 1D- and 2D-NMR, and high-resolution mass spectrometry data. Compounds 5 and 6 showed moderate bioactivities against BCG with MIC values of 40 and 20 μg/mL, respectively.

Funding

This work was supported by grants from the National Key R&D Program of China (2018YFC0311002, 2017YFD0201203, 2017YFC1601300), the National Natural Science Foundation of China (31430002, 3132010391, 31600136), and the Fundamental Research Funds for the Central Public Welfare Research Institutes (Z0547).

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