lsyc_a_908310_sm4573.pdf (816.84 kB)
Oxidative Coupling of o-Phenylenediamine with Arylmethylamines to Synthesize Aryl-Substituted Benzimidazoles Under Catalyst-Free and Solvent-Free Conditions
Version 3 2014-07-09, 01:13
Version 2 2014-07-09, 01:13
Version 1 2014-07-09, 01:13
journal contribution
posted on 2014-07-09, 01:13 authored by Jiatao Yu, Ming LuSolvent-free oxidative synthesis of benzimidazoles from arylmethylamines and o-phenylenediamine has been achieved under catalyst-free conditions. This reaction can use tert-butyl hydroperoxide (TBHP) as the oxidant, and a wide variety of derivatives were obtained in good yields. The reaction mechanism was proposed and this method provides a direct and practical approach for the preparation of substituted benzimidazoles.