lsyc_a_886330_sm1770.pdf (2.28 MB)
Rapid and Efficient Synthesis of 3,3-Di(1H-indol-3-yl)indolin-2-ones and 2,2-Di(1H-indol-3-yl)-2H-acenaphthen-1-ones Catalyzed by p-TSA
Version 2 2014-06-09, 18:53
Version 1 2014-06-09, 18:53
journal contribution
posted on 2014-06-09, 18:53 authored by Jiangxia Yu, Tianhua Shen, Yan Lin, Yongbing Zhou, Qingbao SongAn efficient synthesis of 3,3-di(1H-indol-3-yl)indolin-2-ones and 2,2-di(1H-indol-3-yl)-2H-acenaphthen-1-ones via a reaction of various isatins or acenaphthenequinone with indoles in the presence of p-methylbenzene sulfonic acid (p-TSA) in CH2Cl2 at room temperature is described. The advantages of this method include good reaction yield, simple workup procedure, and mild reaction condition.