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Regioselective Synthesis of Unsymmetrical 3-(Quinolin-3-yl)Pentane-1,5-Diones in the Aqueous Medium through Montmorillonite KSF Catalysis
journal contribution
posted on 2020-05-04, 06:55 authored by Eethamukkala Ubba, Fazlur-Rahman Nawaz KhanIn the presence of heterogeneous catalyst Montmorillonite KSF (M-KSF) 2-chloro-3-formyl quinolines, 1 were successfully converted into regioselective 3-(quinolin-3-yl)pentane-1,5-diones, 3. A one-pot sequential reaction (aldol-condensation-Michael addition) of distinct acetophenones, 2 was efficient in an aqueous medium.