Solvent free synthesis of 1-alkoxyphosphonium chlorides for stereoselective multipurpose vinyl ethers

An efficient solvent free method is developed for the preparation of structurally diverse 1-alkoxymethylphosphonium chlorides in high yield. One of the prepared salts derived from (1 R,2S,5R)-(−)-Menthol auxiliary was further employed for the synthesis of vinyl ethers, where up to 99% stereoselectivity was achieved.