Synthesis and spectral characterization of metal complexes of Schiff base derived from indole-3-carboxaldehyde and L-histidine as potent biocides
This research work presents the structural features and biological activities of a novel series of Mn/Fe/Co/Ni/Cu/Zn(II)-(indal-L-his) complexes obtained from indole-3-carboxaldehyde (indal) and L-histidine (L-his). The prepared compounds were characterized by elemental analysis, molar conductivity, magnetic, IR, UV–vis, 1H NMR, mass and ESR spectroscopies, powder XRD and TGA studies. Electronic spectra and magnetic moment data suggest an octahedral geometry for [Mn(II)-(indal-L-his)2(H2O)2] and [Fe(II)-(indal-L-his)2(H2O)2], tetrahedral geometry for [Co(II)-(indal-L-his)2] and [Zn(II)-(indal-L-his)2] and square planar geometry were assigned for [Ni(II)-(indal-L-his)2] and [Cu(II)-(indal-L-his)2]. The photocatalytic efficiency was explored for the synthesized compounds. In vitro antimicrobial activity of synthesized compounds was analyzed against some selected Gram-positive and Gram-negative bacterial and fungal species by disc diffusion technique. The compounds have shown to reveal excellent antibacterial and antifungal activity.
